| Gene Symbol | PGAP2 |
| Full Name | Post-GPI Attachment to Proteins 2 |
| Protein Type | Enzyme |
| Function | encodes an essential enzyme involved in the remodeling of glycosylphosphatidylinositol (GPI) anchors after their attachment to proteins in the endoplasmic reticulum. |
| Molecular Weight | 40 kDa |
| Ensembl ID | ENSG00000132581 |
| GeneCards | PGAP2 |
| Human Protein Atlas | PGAP2 |
| Glucosamine (GlcN) | Core sugar linking to phosphatidylinositol |
| Mannose (Man) residues | Three mannose units in the core |
| Phosphoethanolamine | Bridge to the protein C-terminus |
| Lipid moiety | Typically diacylglycerol or ceramide |
| Deacylation | Removes an acyl chain from the inositol ring |
| Acyl exchange | Replaces fatty acids to optimize membrane integration |
| Chain length selection | Prefers unsaturated long-chain fatty acids |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!