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gene 3,956 words KG: NDUFAF3
Contents

NDUFAF3 Gene

🧬 Gene Info
Gene SymbolNDUFAF3
Full NameNADH Dehydrogenase Complex Assembly Factor 3
Chromosome3p21.31
Functionencodes a critical mitochondrial assembly factor required for the proper assembly and function of complex I (NADH:ubiquinone oxidoreductase) of the mitochondrial electron transport chain[@saada2009...
Primary ExpressionHigh in brain, heart, muscle (high energy tissues)
Molecular Weight22 kDa
Amino Acids198 aa
UniProt ID[Q9P0U4](https://www.uniprot.org/uniprot/Q9P0U4)
Ensembl IDENSG00000163293
OMIM618196
GeneCardsNDUFAF3
Human Protein AtlasNDUFAF3
Associated Diseasesneurodegeneration
KG Connections5 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (16)

CYP46A1 Overexpression Gene Therapy
Score: 0.92Senescent Cell Mitochondrial DNA Release
Score: 0.74Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70Mitochondrial Transfer Pathway Enhancement
Score: 0.70Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67Mitochondrial RNA Granule Rescue Pathway
Score: 0.66Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62Digital Twin-Guided Metabolic Reprogramming
Score: 0.55Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (5 edges)

NDUFAF3 associated_with RHOH
NDUFAF3 associated_with CDK10
NDUFAF3 associated_with MC1R
GTPBP3 associated_with NDUFAF3
NDUFAF3 associated_with ERBB3

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