| Gene Symbol | MAPK6 |
| Full Name | Mitogen-Activated Protein Kinase 6 |
| Protein Type | Kinase |
| Function | is an atypical member of the MAP kinase family. |
| Primary Expression | neurons and glial cells where it modulates neuronal development, cognitive function, and responses to neurotoxic stress |
| Subcellular Localization | **: Nuclear-cytoplasmic shuttling regulates its access to substrates |
| Amino Acids | 721 aa |
| Pathways | MAPK |
| Ensembl ID | ENSG00000170048 |
| GeneCards | MAPK6 |
| Human Protein Atlas | MAPK6 |
| Cytoskeletal dynamics | Through phosphorylation of proteins involved in actin remodeling |
| Stress response | Activation of p38 MAPK pathway effectors |
| Gene expression | Through transcription factor phosphorylation |
| Cell cycle progression | Regulation of G1/S transition |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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