| Gene Symbol | MAP4 |
| Chromosome | 3p21.31 |
| Protein Type | Gene |
| Function | Microtubule-associated protein 4 (MAP4) is a cytoskeletal protein that binds to microtubules and regulates their stability, dynamics, and interaction with other cellular components. |
| Primary Expression | non-neuronal cells but is also present in neurons where it interacts with tubulin to promote microtubule assembly and protect aga |
| Molecular Weight | 210 kDa |
| Amino Acids | 1862 aa |
| UniProt ID | P27816 |
| GeneCards | MAP4 |
| Human Protein Atlas | MAP4 |
| Tau protein | Primary neuronal MAP with which MAP4 shares regulatory pathways |
| MAP2 | Classical neuronal microtubule-associated protein |
| Tubulin | Core microtubule component with which MAP4 directly interacts |
| GSK-3β | Kinase regulating MAP4 phosphorylation |
| Axonal transport | Critical process requiring MAP4-mediated microtubule stability |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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