| Gene Symbol | LAPTM5 |
| Full Name | Lysosomal associated transmembrane protein 5 |
| Chromosome | 1p35.1 |
| Function | The protein interacts with components of the lysosomal trafficking machinery, including |
| Subcellular Localization | lysosomes and the endoplasmic reticulum. LAPTM5 is a member of the LAPTM family of proteins that play critical roles in |
| Amino Acids | 397 aa |
| UniProt ID | [Q9Y5W7](https://www.uniprot.org/uniprot/Q9Y5W7) |
| Ensembl ID | ENSG00000125351 |
| GeneCards | LAPTM5 |
| Human Protein Atlas | LAPTM5 |
| N-terminal cytoplasmic domain | Contains sorting motifs (YXXΦ) for lysosomal targeting |
| Transmembrane regions | Four predicted transmembrane helices |
| C-terminal cytoplasmic tail | Contains regulatory motifs for protein interactions |
| V-ATPase | Maintains lysosomal acidification necessary for enzymatic activity[@laptm2020] |
| Vesicular traffic proteins | Facilitates transport of cargo between intracellular compartments |
| Associated Diseases | Neurodegeneration, ALS through: |
| Databases | GeneCardsNCBI GeneHPASTRING |
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