| Gene Symbol | KDM3B |
| Full Name | Lysine Specific Demethylase 3B |
| Aliases | Page for KDM3B, Lysine Specific Demethylase 3B (JHDM2B |
| Chromosome | 5q31.1 |
| Protein Family | JHDM3/KDM3 family (Jumonji C domain demethylase) |
| Function | is a Jumonji C (JmjC) domain-containing histone demethylase that catalyzes the removal of methyl groups from histone lysine residues. |
| Primary Expression | multiple brain regions: |
| UniProt ID | Q7Z6W4 |
| NCBI Gene ID | 55693 |
| Ensembl ID | ENSG00000106479 |
| OMIM | 607395 |
| GeneCards | KDM3B |
| Human Protein Atlas | KDM3B |
| H3K9me1/2 | Primary substrate — demethylation activates gene expression |
| H3K9me3 | Also targeted, particularly in transcriptional activation |
| Associated Diseases | Childhood Interstitial Lung Disease, Litter Size, Live Lamb Number, Live Lamb Rate, Pregnancy Duration, Pulmonary Arterial Hypertension |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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