gene 815 words KG: HTR1F
Contents

5-Hydroxytryptamine Receptor 1F

🧬 Gene Info
Gene SymbolHTR1F
Full Name5-Hydroxytryptamine Receptor 1F
Chromosome3p12
Protein TypeReceptor
Functionencodes the 5-HT1F serotonin receptor, a Gi/Go-coupled GPCR that inhibits adenylate cyclase activity
Primary Expressionthe trigeminal ganglion and brain, where it modulates nociception and migraine
Molecular Weight39 kDa
UniProt IDP30939
NCBI Gene ID3354
Ensembl IDENSG00000140022
OMIM182134
GeneCardsHTR1F
Human Protein AtlasHTR1F
N-terminal extracellular domainContains conserved disulfide bond
Seven transmembrane domainsα-helices connected by three extracellular and three intracellular loops
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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