| Gene Symbol | GSSGENE |
| Aliases | GSSGENE |
| Chromosome | 20q11.22 |
| Function | ### Glutathione Biosynthesis |
| N-terminal domain | Binding site for γ-glutamylcysteine |
| C-terminal domain | Binding site for glycine and ATP |
| Active site | Catalytic residues including Asp487, Lys329, and Glu432 |
| Direct antioxidant | GSH directly scavenges reactive oxygen species (ROS) and electrophiles |
| Detoxification | GSH conjugates to xenobiotics via glutathione S-transferases |
| Redox buffer | The GSH/GSSG ratio maintains cellular redox potential |
| Protein maintenance | GSH prevents protein thiol oxidation and misfolding |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!