| Gene Symbol | GABBR1 |
| Full Name | Gamma-Aminobutyric Acid Type B Receptor Subunit 1 |
| Chromosome | 6p21.31 |
| Function | encodes the GABA-B1 subunit of the metabotropic GABA receptor |
| Primary Expression | Cerebral cortex, Hippocampus, Cerebellum, Thalamus, Basal ganglia |
| Amino Acids | 960 aa |
| UniProt ID | Q9UBS5 |
| NCBI Gene ID | 2550 |
| Ensembl ID | ENSG00000204681 |
| OMIM | 603540 |
| GeneCards | GABBR1 |
| Human Protein Atlas | GABBR1 |
| Ligand recognition | The N-terminal venus flytrap domain (VFT) binds GABA and pharmacological agonists (baclofen) with high affinity |
| Receptor assembly | The coiled-coil domain at the C-terminus mediates obligate heterodimerization with GABBR2 |
| Synaptic localization | Contains an ER retention signal (RSRR) that is masked upon GABBR2 binding, enabling surface trafficking |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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