| Gene Symbol | CDR2 |
| Aliases | Cerebellar Degeneration-Related Protein 2 |
| Chromosome | 12p13 |
| Protein Type | Gene |
| Function | is a cytoplasmic antigen that serves as the primary autoantibody target in paraneoplastic cerebellar degeneration (PCD), a rare autoimmune disorder affecting the cerebellum. |
| Primary Expression | neural tissue |
| Molecular Weight | 55 kDa |
| Amino Acids | 520 aa |
| GeneCards | CDR2 |
| Human Protein Atlas | CDR2 |
| Cerebellar cortex | Highest expression in Purkinje cell bodies and dendrites |
| Hippocampus | Moderate expression in pyramidal neuron layers |
| Cerebral cortex | Lower expression in layer 5 pyramidal neurons |
| Brainstem | Expression in specific nuclei including the inferior olive |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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