gene 2,335 words KG: ARF3
Contents

ARF3 Gene

🧬 Gene Info
Gene SymbolARF3
Full NameADP Ribosylation Factor 3
Chromosome12q13.13
Functionis a member of the ARF family of small GTPases that function as molecular switches in intracellular membrane trafficking.
Subcellular LocalizationIn neurons, ARF3 localizes to multiple compartments:
Molecular Weight20 kDa
Amino Acids181 aa
UniProt IDP61203
Ensembl IDENSG00000100103
OMIM171745
GeneCardsARF3
Human Protein AtlasARF3
Presynaptic TerminalsARF3 regulates synaptic vesicle trafficking, including vesicle pooling, release, and recycling
Dendritic SpinesARF3 controls spine morphogenesis and AMPA receptor trafficking through endosomal pathways [11/https://doi.org/10.1242/jcs.078501)
Soma and DendritesARF3 participates in general membrane trafficking and protein sorting
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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