| Gene Symbol | APEX1 |
| Full Name | Apurinic/Apyrimidinic Endodeoxyribonuclease 1 |
| Chromosome | 14q11.2 |
| Function | Damage Recognition: DNA glycosylases (e.g., OGG1, NTH1) recognize and remove damaged bases |
| Primary Expression | neurons throughout the brain: |
| Molecular Weight | 36.5 kDa |
| Amino Acids | 318 aa |
| Exons | 5 exons |
| UniProt ID | [P27635](https://www.uniprot.org/uniprot/P27635) |
| Ensembl ID | ENSG00000100813 |
| GeneCards | APEX1 |
| Human Protein Atlas | APEX1 |
| Gene length | ~2.9 kb coding sequence |
| Promoter | TATA-less, GC-rich with multiple transcription factor binding sites |
| Molecular weight | ~36.5 kDa |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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