gene 1,902 words KG: ANO8
Contents

ANO8 (Anoctamin 8)

🧬 Gene Info
Gene SymbolANO8
AliasesTMEM16H
Chromosome19p13.3
Protein FamilyAnoctamin (TMEM16) family
Functionis a member of the anoctamin family of calcium-activated chloride channels (CaCCs).
Primary Expressionvarious tissues including the brain, lung, testis, and cardiovascular system, with particularly notable expression in neuronal tissues where it partic
Amino Acids823 aa
UniProt IDQ3YPP3
NCBI Gene ID57727
Ensembl IDENSG00000156469
OMIM607684
GeneCardsANO8
Human Protein AtlasANO8
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66

Related Analyses (4)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
mitochondrial-dysfunction-neurodegeneration-comparison
disease · Pages share 4 hypotheses
Familial vs Sporadic Neurodegeneration Comparison
disease · Pages share 4 hypotheses
UPenn Observational Research Repository (NCT04715399)
clinical · Pages share 4 hypotheses
TARDBP Mutations in Amyotrophic Lateral Sclerosis
disease · Pages share 4 hypotheses

Knowledge Graph (2 edges)

ANO8 data_in benchmark_ot_ad_answer_key:ANO8
benchmark_ot_ad_answer_key:ANO8 data_in ANO8

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.