disease 1,306 words KG: Somatosensory Deficits in Corticobasal Syndrome
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Somatosensory Deficits in Corticobasal Syndrome

Disease Info
Intact primary modalitiesLight touch, pain, temperature, and vibration sense are often normal
Impaired sensory discriminationLoss of ability to distinguish the quality of stimuli
PatternTypically affects the hand and arm contralateral to the affected hemisphere
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Related Hypotheses (24)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.95
Chromatin Accessibility Restoration via BRD4 Modulation
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SASP-Mediated Cholinergic Synapse Disruption
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Targeted APOE4-to-APOE3 Base Editing Therapy
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SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Aquaporin-4 Polarization Rescue
Score: 0.73
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.71
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69
R-Loop Resolution Enhancement Therapy
Score: 0.68
Osmotic Gradient Restoration via Selective AQP1 Enhancement
Score: 0.68
Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli
Score: 0.67
Complement C1q Subtype Switching
Score: 0.66
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Sphingolipid Metabolism Reprogramming
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
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Related Analyses (19)

Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

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Somatosensory Deficits in Corticobasal Syndrome type_of neurodegenerative_diseases

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