disease 1,267 words KG: Cholinergic Dysfunction in Corticobasal Syndrome
Contents

Cholinergic Dysfunction in Corticobasal Syndrome

Disease Info
Primary SiteBasal forebrain (nucleus basalis of Meynert)
Imaging MarkerReduced AchE activity on PET, volumetric MRI changes
Clinical CorrelationAttention, executive dysfunction, neuropsychiatric symptoms
Therapeutic ImplicationCholinesterase inhibitors may provide modest benefit
DifferentiationMore severe cholinergic loss than PSP, less than AD
KG Connections1 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

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