| Gene Symbol | ent-gene-41a40502 |
| Function | ### HPA Axis Activation |
| Subcellular Localization | subset of neurons |
| Parvocellular division | The primary location of CRH neurons |
| Dorsal cap | Contains stress-responsive CRH neurons |
| Periventricular zone | Adjacent to the third ventricle |
| Lateral PVN | Integration with autonomic regions |
| Small cell bodies | Parvocellular neurons (10-15 μm diameter) |
| Dendritic arborization | Extensive dendritic trees for input integration |
| Axonal projections | To median eminence and brainstem |
| Dense core vesicles | Contain neuropeptides for release |
| Physical stressors | Pain, infection, hemorrhage |
| Psychological stressors | Fear, novelty, social conflict |
| Metabolic stressors | Hypoglycemia, hypoxia |
| Circadian cues | Morning cortisol surge |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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