cell 935 words KG: ent-gene-e5eb32bf
Contents

LHX6-Positive Neurons

🔬 Protein Info
Gene SymbolLHX6
Full NamePositive Neurons
Chromosome9q33
Protein TypeTranscription Factor
Functionencodes a LIM-type homeobox transcription factor that plays a fundamental role in the development of GABAergic inhibitory interneurons in the mammalian forebrain.
Primary Expressionspecific interneuron populations, where it maintains aspects of interneuron identity and function
Molecular Weight43.8 kDa
Amino Acids406 aa
PathwaysShh, BMP, Wnt
UniProt IDQ9R0E3
NCBI Gene ID26468
Ensembl IDENSG00000106852
OMIM608139
GeneCardsLHX6
Human Protein AtlasLHX6
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Related Hypotheses (8)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
...
Score: 0.68

Related Analyses (11)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-e5eb32bf data_in benchmark_ot_ad_answer_key:LHX6
benchmark_ot_ad_answer_key:LHX6 data_in ent-gene-e5eb32bf

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