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cell 871 words KG: ent-gene-06beb203
Contents

IGF-1 Receptor Neurons

🔬 Protein Info
Gene SymbolIGF
Full Name1 Receptor (IGF1R) Neurons
Chromosome15q26.3
Function- Oligodendrocyte survival: Via IGF1R signaling
GeneCardsIGF
Human Protein AtlasIGF
Associated DiseasesAls, Fibrosis, Aging, Neurodegeneration, Cancer, Amyotrophic Lateral Sclerosis
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (8)

APOE-Dependent Autophagy Restoration
Score: 0.85Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84Senescent Cell Mitochondrial DNA Release
Score: 0.74Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72

Related Analyses (13)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archivedGene expression changes in aging mouse brain predicting neur
neurodegeneration · completedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archived

Related Experiments (4)

In vivo IGF-I intravitreal injection in rd10 mice
validation · proposed · Score: 0.90Ex vivo IGF-I treatment in rd10 organotypic retinal explants
validation · proposed · Score: 0.90Microglial depletion study using clodronate liposomes
exploratory · proposed · Score: 0.85Cognitive Reserve Mechanisms in Alzheimer's Disease — Molecu
clinical · proposed · Score: 0.40

Knowledge Graph (2 edges)

ent-gene-06beb203 data_in benchmark_ot_ad_answer_key:IGF1R
benchmark_ot_ad_answer_key:IGF1R data_in ent-gene-06beb203

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