cell 901 words KG: ent-gene-fc3f87ca
Contents

mGluR3 (GRM3) Neurons

🔬 Protein Info
Gene Symbolent-gene-fc3f87ca
Cerebral CortexLayer-specific expression in pyramidal neurons, particularly in layers II/III and V
HippocampusPredominant expression in CA1-CA3 pyramidal neurons and dentate gyrus granule cells
Basal GangliaModerate expression in striatal medium spiny neurons
ThalamusExpression in relay neurons of various thalamic nuclei
CerebellumPresent in Purkinje cells and granule cells
Substantia NigraExpression in dopaminergic neurons of the pars compacta
PresynapticLocated on axon terminals where it acts as an autoreceptor modulating glutamate release
PostsynapticLocated on dendritic spines and shafts regulating neuronal excitability
GlialStrong expression on astrocytes and oligodendrocyte precursor cells
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (12)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · completed
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-fc3f87ca data_in benchmark_ot_ad_answer_key:GRM3
benchmark_ot_ad_answer_key:GRM3 data_in ent-gene-fc3f87ca

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