| Gene Symbol | ent-gene-41a40502 |
| Morphology | corticotropin-releasing neuron (source: Cell Ontology) |
| Central amygdala | Stress and emotional processing |
| Barrington's nucleus | Micturition reflex control |
| Cerebral cortex | Cognitive and emotional integration |
| Hippocampal formation | Memory and stress interaction |
| Locus coeruleus | Norepinephrine system modulation |
| CRH (CRF) | Primary ligand, 41 amino acids |
| CRHbp | CRH-binding protein, modulates CRH availability |
| UCN1, UCN2, UCN3 | Urocortin peptides with CRH-like effects |
| CRHR1 | High affinity for CRH, primary signaling receptor |
| CRHR2 | Lower affinity, often mediating different effects |
| HPA axis activation | CRH stimulates ACTH release from anterior pituitary corticotrophs |
| Glucocorticoid feedback | Cortisol negatively feeds back on CRH neurons |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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