cell 856 words KG: ent-gene-36cfc914
Contents

Arcuate Nucleus TH Neurons

🔬 Protein Info
Gene Symbolent-gene-36cfc914
Function### Metabolic Regulation
Neurochemical phenotypeCo-express TH, aromatic L-amino acid decarboxylase (AADC), and often dopamine transporter (DAT)
ElectrophysiologyExhibit pacemaker-like firing properties with calcium-dependent oscillations
MorphologyMedium-sized soma with extensive dendritic arborizations
Metabolic couplingRespond to peripheral metabolic signals including leptin, insulin, and glucose
Co-neurotransmittersSome co-express neuropeptide Y (NPY), galanin, or other peptides
Projection patternsDistinct populations project to different brain regions
Metabolic statusDifferent responsiveness to energy state changes
Prolactin secretionDopaminergic inhibition of prolactin release
Growth hormone regulationModulate GH release through hypothalamic pathways
Reproductive functionInfluence GnRH secretion and reproductive behavior
Stress responsesCoordinate metabolic and endocrine stress responses
Blood pressureModulate sympathetic tone
Heart rateInfluence cardiac vagal and sympathetic activity
Vasomotor toneControl peripheral vascular resistance
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (12)

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Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived

Knowledge Graph (2 edges)

ent-gene-36cfc914 data_in benchmark_ot_ad_answer_key:TH
benchmark_ot_ad_answer_key:TH data_in ent-gene-36cfc914

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