| Gene Symbol | BIOMARKERS |
| Elevation in 4R tauopathies | Moderate elevations (typically 300-500 pg/mL) observed in both CBD and PSP, lower than AD levels |
| Diagnostic utility | Less specific than p-tau but provides information on disease severity |
| Correlation | Levels often correlate with disease progression and cortical atrophy |
| Longitudinal changes | t-tau shows gradual increase over disease course, tracking neurodegeneration |
| Associated Diseases | Neurocognitive Disorders, Prostate Cancer, ALS, Frailty, Hepatocellular Carcinoma, Inclusion Body Myositis |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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