| Gene Symbol | APBB2 |
| Aliases | APBB2PROTEIN |
| Function | APBB2 is also known by several alternative names, including APP-binding protein 2, TIP-B1, and FE65-like protein. |
| Subcellular Localization | in the cytoplasm and nucleus, where it plays critical roles in cellular signalin |
| Molecular Weight | 76 kDa |
| Pathways | Cholesterol |
| GeneCards | APBB2 |
| Human Protein Atlas | APBB2 |
| WW Domain | Present at the N-terminus, this domain binds to proline-rich motifs and mediates interactions with various signaling proteins. |
| C-terminal Proline-Rich Region | Contains multiple PXXP motifs that facilitate interactions with SH3 domain-containing proteins involved in signaling cascades. |
| Associated Diseases | ALS, Alzheimer, neurodegeneration |
| Interactions | APOE, LRP1 |
| KG Connections | 12 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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