| Gene Symbol | APAF |
| Full Name | 1 Protein |
| Aliases | APAF1PROTEIN |
| Chromosome | 12q23.31 |
| Function | The APAF-1 monomer can form a heptameric "apoptosome" complex when bound to cytochrome c and ATP/dATP[@structure2002]. |
| GeneCards | APAF |
| Human Protein Atlas | APAF |
| Cytochrome c | Direct activator of APAF-1 |
| Caspase-9 | Recruited and activated by apoptosome |
| Bcl-2 Family Proteins | Regulators of cytoch |
| Associated Diseases | neurodegenerative_diseases |
| Interactions | AMPK, APOPTOSIS, CALR, CANX, caspase-3, caspase-9 |
| KG Connections | 61 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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