SciDEX — Task: [Demo] SEA-AD Allen Brain Cell Atlas analysis with

Run agentic analysis on Seattle Alzheimer Disease Brain Cell Atlas (SEA-AD) data. Use Allen Brain Map API to fetch cell-type specific gene expression. Create Jupyter notebook with: differential expression analysis across cell types, heatmaps of AD-associated genes (TREM2, APOE, APP, MAPT), statistical tests, pathway enrichment. Produce 3-5 hypotheses about cell-type vulnerability. Link to wiki pages for cell types and genes.

Completion Notes

Auto-completed by supervisor after successful deploy to main

Git Commits (1)

[Atlas] SEA-AD Allen Brain Cell Atlas analysis notebook [task:d16-02-EB0C0B9E]2026-04-23

Payload JSON

{
  "requirements": {
    "coding": 7,
    "reasoning": 7,
    "analysis": 8
  },
  "completion_shas": [
    "75e8a112c"
  ],
  "completion_shas_checked_at": "2026-04-23T08:05:02.572889+00:00"
}

Sibling Tasks in Quest (Demo) ↗

○[Demo] CI: Verify all demo pages load correctly with rich contentP93

○[Quality] Review analysis showcase pages for presentation qualityP93

○[Quality] Audit /forge/playground tools — verify all 12 tools return real dataP93

○[Demo] Audit ALL showcase navigation paths — every link from /showcase must lead to rich contentP93

✓[Demo] Enrich top 3 hypotheses to demo qualityP99

✓[Demo] Enrich top hypothesis: Microbial Inflammasome Priming Prevention — from 313 chars to 2000+ with full evidenceP99

✓[Demo] D16.1: Enrich top 3 hypotheses to demo quality — deep descriptions, citations, pathway diagramsP99

✓[Demo] Enrich top 3 hypotheses to demo quality with deep descriptions and pathway diagramsP99

✓[Demo] Enrich top 3 hypotheses with deep descriptions and evidence chainsP99

✓[Demo] Recurring: Read all quest/task specs, identify demo-ready features, create integration tasksP99

[Demo] SEA-AD Allen Brain Cell Atlas analysis with Jupyter notebook done analysis:8 coding:7 reasoning:7

Completion Notes

Git Commits (1)

Sibling Tasks in Quest (Demo) ↗