LAMP2B

Score: 0.263 Price: $0.26 Undruggable Druggability Status: active

HYPOTHESES

PAPERS

KG EDGES

DEBATES

3D Protein Structure

🔮 LAMP2B — AlphaFold P13473 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Druggability & Clinical Context

Druggability

Undruggable

Score: 0.20

Clinical Stage

Preclinical

Target Class

Signaling Protein

Safety

0.30

Druggability Analysis

Drug Development0.00

Structural Tractability0.30

Target Class0.50

Safety Profile0.30

Key Metrics

PDB Structures:

Known Drugs:

Approved:

In Clinical Trials:

Mechanism: Prioritized from 1 SciDEX hypotheses, including: Microglia-Derived Extracellular Vesicle Engineering for Targeted Mitochondrial Delivery

Known Drugs:

No known drugs targeting this protein

Structural Data:

PDB —AlphaFold ✓Cryo-EM —

UniProt: P13473

🔮 Predicted Protein Structure (AlphaFold)

🔮 LAMP2B — AlphaFold P13473 Click to expand interactive 3D viewer

AI-predicted structure from AlphaFold EBI | Powered by Mol* | Rotate: click+drag | Zoom: scroll

3D Protein Structure (AlphaFold)

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AlphaFold predicted structure available for P13473

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Linked Hypotheses (0)

No linked hypotheses

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Knowledge Graph (20)

associated with (2)

LAMP2B→neurodegenerationLAMP2B→RAB27A

co discussed (8)

ChR2→LAMP2BBNIP3L→LAMP2BRHOT1→LAMP2BPANX1→LAMP2BRAB27A→LAMP2B

▸ Show 3 more

BNIP3→LAMP2BLAMP2B→Synthetic fusion proteinsLAMP2B→GJA1

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