Cas13 gRNA Design for Silencing MAPT (Tau) Transcripts in Alzheimer's Disease — Analysis Notebook

CI-generated notebook stub for analysis SDA-BIOMNI-CAS13_PR-d6f415f0. Can optimized Cas13 guide RNAs selectively silence pathogenic MAPT splice variants (4R-tau) while preserving normal 3R-tau expression in neurons?