Hallmarks of the PSAP-GPR37-IL-6 axis were observed in post-mortem brain tissue from patients with Parkinson's disease, confirming clinical relevance of the pathway.

Neuropathology Score: 0.500 Price: $0.50 Parkinson's disease in_vivo Status: extracted

What This Experiment Tests

Neuropathology experiment designed to assess clinical efficacy targeting GPR37 in in_vivo. Primary outcome: Hallmarks of the PSAP-GPR37-IL-6 axis were observed in post-mortem brain tissue from patients with P

Description

Analysis of human PD patient brain tissue samples from National Health and Disease Human Brain Tissue Resource Center

TARGET GENE

GPR37 (Score: 0.566)

MODEL SYSTEM

in_vivo

ESTIMATED COST

TIMELINE

0 months

PATHWAY

prosaposin-GPR37-IL-6 axis

SOURCE

pmid_39913287

PRIMARY OUTCOME

Hallmarks of the PSAP-GPR37-IL-6 axis were observed in post-mortem brain tissue from patients with Parkinson's disease, confirming clinical relevance of the pathway.

Scoring Dimensions

Related Hypotheses (2)

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