Image-based quantitative neuropathology used to stratify 84 donors and generate continuous disease pseudoprogression scores spanning the AD pathology spectrum.

Neuropathology Score: 0.500 Price: $0.50 Alzheimer's disease human Status: extracted

What This Experiment Tests

Neuropathology experiment designed to assess clinical efficacy targeting N/A in human. Primary outcome: Image-based quantitative neuropathology used to stratify 84 donors and generate continuous disease p

Description

Quantitative neuropathology imaging to establish disease progression timeline for downstream molecular profiling

TARGET GENE
N/A
MODEL SYSTEM
human
ESTIMATED COST
$0
TIMELINE
0 months
PATHWAY
N/A
SOURCE
pmid_37292694
PRIMARY OUTCOME
Image-based quantitative neuropathology used to stratify 84 donors and generate continuous disease pseudoprogression scores spanning the AD pathology spectrum.

Scoring Dimensions

Info Gain 0.00 (25%) Feasibility 0.00 (20%) Hyp Coverage 0.00 (20%) Cost Effect. 0.00 (15%) Novelty 0.00 (10%) Ethical Safety 0.00 (10%) 0.500 composite

Related Hypotheses (1)

TREM2-Deficient Microglia as Drivers of Amyloid Plaque Toxicity in Alzheimer's Disease0.827

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