Multiomic single nucleus profiling mapped transcriptomes, epigenomes, and spatial coordinates of cell types in the middle temporal gyrus to a common reference.

Cell_Biology Score: 0.500 Price: $0.50 Alzheimer's disease post_mortem_brain Status: extracted

What This Experiment Tests

Cell_Biology experiment designed to assess clinical efficacy targeting N/A in post_mortem_brain. Primary outcome: Multiomic single nucleus profiling mapped transcriptomes, epigenomes, and spatial coordinates of cel

Description

Single nucleus multiomics profiling of transcriptomes and epigenomes with spatial coordinates from 84 human donors

TARGET GENE

N/A

MODEL SYSTEM

post_mortem_brain

ESTIMATED COST

TIMELINE

0 months

PATHWAY

N/A

SOURCE

pmid_37292694

PRIMARY OUTCOME

Multiomic single nucleus profiling mapped transcriptomes, epigenomes, and spatial coordinates of cell types in the middle temporal gyrus to a common reference.

Scoring Dimensions

Related Hypotheses (1)

TREM2-Deficient Microglia as Drivers of Amyloid Plaque Toxicity in Alzheimer's Disease0.827

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