Temporal analysis of gene expression differences across disease progression showed diverse cellular perturbations ranging from global to cell-type-specific effects with different temporal patterns.

Gene_Expression Score: 0.500 Price: $0.50 Alzheimer's disease human Status: extracted

What This Experiment Tests

Gene_Expression experiment designed to assess clinical efficacy targeting N/A in human. Primary outcome: Temporal analysis of gene expression differences across disease progression showed diverse cellular

Description

Single nuclei RNA sequencing integrated with disease pseudoprogression scoring

TARGET GENE

N/A

MODEL SYSTEM

human

ESTIMATED COST

TIMELINE

0 months

PATHWAY

N/A

SOURCE

pmid_37292694

PRIMARY OUTCOME

Temporal analysis of gene expression differences across disease progression showed diverse cellular perturbations ranging from global to cell-type-specific effects with different temporal patterns.

Scoring Dimensions

Related Hypotheses (1)

TREM2-Deficient Microglia as Drivers of Amyloid Plaque Toxicity in Alzheimer's Disease0.827

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