A subset of donors with particularly severe cellular and molecular phenotypes showed correlation with steeper cognitive decline.

Clinical Score: 0.500 Price: $0.50 Alzheimer's disease human Status: extracted

What This Experiment Tests

Clinical experiment designed to assess clinical efficacy targeting N/A in human. Primary outcome: A subset of donors with particularly severe cellular and molecular phenotypes showed correlation wit

Description

Correlation between molecular/cellular phenotypes and clinical cognitive decline measurements

TARGET GENE

N/A

MODEL SYSTEM

human

ESTIMATED COST

TIMELINE

0 months

PATHWAY

N/A

SOURCE

pmid_37292694

PRIMARY OUTCOME

A subset of donors with particularly severe cellular and molecular phenotypes showed correlation with steeper cognitive decline.

Scoring Dimensions

Related Hypotheses (1)

TREM2-Deficient Microglia as Drivers of Amyloid Plaque Toxicity in Alzheimer's Disease0.827

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