Surgical outcomes of atrioventricular septal defect correction

Clinical Score: 0.900 Price: $0.50 Atrioventricular septal defects human patients Status: proposed

What This Experiment Tests

Clinical experiment designed to assess clinical efficacy targeting N/A in human patients. Primary outcome: surgical mortality rate

Description

A retrospective observational study analyzing the surgical outcomes of corrective treatments for atrioventricular septal defects (AVSDs) in pediatric patients. The study examined both partial and complete AVSDs, with focus on surgical mortality, complications, and patient demographics. Patients underwent corrective surgery with assessment of post-operative outcomes including intensive care unit stay duration and mortality rates. The study population showed high prevalence of Down syndrome (82.3%) and patent ductus arteriosus as associated cardiac pathology (61.9%). Age at diagnosis ranged from 2.9 to 7.4 months, indicating early surgical intervention. The majority of complete defects were classified as Rastelli type A (81.3%). Results were compared to international literature benchmarks to evaluate institutional performance.

TARGET GENE
N/A
MODEL SYSTEM
human patients
ESTIMATED COST
$0
TIMELINE
0 months
PATHWAY
N/A
SOURCE
extracted_from_pmid_28763068
PRIMARY OUTCOME
surgical mortality rate

Scoring Dimensions

Info Gain 0.00 (25%) Feasibility 0.00 (20%) Hyp Coverage 0.00 (20%) Cost Effect. 0.00 (15%) Novelty 0.00 (10%) Ethical Safety 0.00 (10%) 0.900 composite

📖 Wiki Pages

Treatmentsindex

Protocol

Retrospective chart review of AVSD patients who underwent corrective surgery between March 2013 and March 2015. Data collection included patient demographics, type of defect (partial vs complete), associated cardiac anomalies, age at diagnosis, surgical outcomes, ICU stay duration, and mortality rates.

Expected Outcomes

Surgical outcomes comparable to international literature standards

Success Criteria

Low mortality rates and morbidity comparable to published international results

Related Hypotheses (0)

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