Quantitative neuropathology characterization of 84 donors revealed stereotyped progression of proteinopathies with inflammatory changes in early disease and neuronal loss in late disease.

Neuropathology Score: 0.500 Price: $0.50 Alzheimer's disease human Status: extracted

What This Experiment Tests

Neuropathology experiment designed to assess clinical efficacy targeting N/A in human. Primary outcome: Quantitative neuropathology characterization of 84 donors revealed stereotyped progression of protei

Description

Neuropathology used to generate pseudoprogression score; cohort comprised 33 male and 51 female donors with average age 88 years at death

TARGET GENE

N/A

MODEL SYSTEM

human

ESTIMATED COST

TIMELINE

0 months

PATHWAY

neuroinflammation

SOURCE

pmid_39402379

PRIMARY OUTCOME

Quantitative neuropathology characterization of 84 donors revealed stereotyped progression of proteinopathies with inflammatory changes in early disease and neuronal loss in late disease.

Scoring Dimensions

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