The Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD) integrates neuropathology, single cell and spatial genomics, and longitudinal clinical metadata to create a multimodal resource for identifyin

Neuropathology Score: 0.500 Price: $0.50 Alzheimer's disease human Status: extracted

What This Experiment Tests

Neuropathology experiment designed to assess clinical efficacy targeting N/A in human. Primary outcome: The Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD) integrates neuropathology, single cell and

Description

Resource creation combining single cell genomics, spatial genomics, neuropathology assessment, and longitudinal clinical data integration for studying Alzheimer's disease pathogenesis

TARGET GENE

N/A

MODEL SYSTEM

human

ESTIMATED COST

TIMELINE

0 months

PATHWAY

N/A

SOURCE

pmid_39402332

PRIMARY OUTCOME

The Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD) integrates neuropathology, single cell and spatial genomics, and longitudinal clinical metadata to create a multimodal resource for identifying cellular and molecular pathologies underlying Alzheimer's disease.

Scoring Dimensions

Related Hypotheses (1)

TREM2-Deficient Microglia as Drivers of Amyloid Plaque Toxicity in Alzheimer's Disease0.827

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