Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about 4e-bp1-protein: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | 4E-BP1 |
| Aliases | Eukaryotic Translation Initiation Factor 4E Binding Protein 1 |
| Protein Family | eIF4E-binding protein family |
| Function | Thr37 and Thr46: Primary mTOR phosphorylation sites; these priming phosphorylations create docking sites for subsequent phosphorylation |
| Primary Expression | Brain (high), heart, skeletal muscle |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | 12.5 kDa |
| Amino Acids | 118 aa |
| UniProt ID | [Q13541](https://www.uniprot.org/uniprot/Q13541) |
| Associated Diseases | Alzheimer's Disease |
| Databases | GeneCardsNCBI GeneHPASTRING |
graph TD
n_4e_bp1_protein["4e-bp1-protein"]
info["No connections yet"]
n_4e_bp1_protein -.-> info
style n_4e_bp1_protein fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7
style info fill:#2a2a2a,stroke:#666,stroke-dasharray:5,color:#999| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
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Experimental studies targeting or related to this entity
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
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Hypotheses and analyses mentioning 4e-bp1-protein in their description or question text
No additional research found