Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PERICYTE-DERIVED EXTRACELLULAR VESICLES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PERICYTE-DERIVED EXTRACELLULAR VESICLES |
graph TD
PERICYTE_DERIVED_EXTRACELLULAR["PERICYTE-DERIVED EXTRACELLULAR VESICLES"]
PERICYTE_DERIVED_EXTRACELLULAR -->|"promotes"| Angiogenesis["Angiogenesis"]
PERICYTE_DERIVED_EXTRACELLULAR -->|"component_of"| ANGPT1["ANGPT1"]
PERICYTE_DERIVED_EXTRACELLULAR -->|"mediates"| Pericyte_Recruitment["Pericyte Recruitment"]
PERICYTE_DERIVED_EXTRACELLULAR -->|"treats"| Sepsis["Sepsis"]
PERICYTE_DERIVED_EXTRACELLULAR -->|"downregulates"| Inflammatory_Cytokines["Inflammatory Cytokines"]
ANGPT1 -->|"expressed in"| PERICYTE_DERIVED_EXTRACELLULAR| Target | Relation | Type | Str |
|---|---|---|---|
| intestinal barrier function | associated_with | phenotype | 0.95 |
| Vascular Barrier Function | associated_with | phenotype | 0.95 |
| Angiogenesis | promotes | process | 0.95 |
| Vascular Permeability | associated_with | phenotype | 0.95 |
| ANGPT1 | transports | protein | 0.90 |
| Pericyte Recruitment | associated_with | process | 0.90 |
| ANGPT1 | associated_with | protein | 0.90 |
| Vascular Permeability | associated_with | phenotype | 0.90 |
| ANGPT1 | component_of | protein | 0.90 |
| Pericyte Recruitment | mediates | process | 0.90 |
| Pericyte Recruitment | associated_with | process | 0.85 |
| Sepsis | treats | disease | 0.85 |
| inflammatory cytokine production | suppresses | process | 0.85 |
| Endothelial Cell Proliferation | promotes | process | 0.85 |
| ANGPT1 | associated_with | protein | 0.85 |
| Sepsis | treats | disease | 0.85 |
| Vascular Barrier Function | associated_with | biological_process | 0.80 |
| Inflammatory Cytokines | downregulates | biomarker | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PERICYTE-DERIVED EXTRACELLULAR VESICLES in their description or question text
No additional research found