Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about microglial activation states: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer'S Disease Progression | regulates | phenotype | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TREM2 | regulates | gene | 0.90 |
| astrocytes | regulates | cell_type | 0.70 |
| SPI1 | regulates | gene | 0.70 |
| SPP1 | associated_with | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| sex-divergent microglial activation states and X-linked immu | 0.626 | neurodegeneration | Sex-Specific Microglial States in Amyloi |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 8 hypotheses Top: 0.861
neurodegeneration | 2026-04-17 | 7 hypotheses Top: 0.685
neurodegeneration | 2026-04-17 | 0 hypotheses
neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.627
neuroinflammation | 2026-04-08 | 7 hypotheses Top: 0.455
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 6 · Score: 0.95 · 2026-04-27
closed · Rounds: 4 · Score: 0.50 · 2026-04-27
closed · Rounds: 4 · Score: 0.64 · 2026-04-26
closed · Rounds: 4 · Score: 0.50 · 2026-04-26
closed · Rounds: 4 · Score: 0.92 · 2026-04-26
closed · Rounds: 4 · Score: 0.69 · 2026-04-21
closed · Rounds: 4 · Score: 0.50 · 2026-04-20
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
closed · Rounds: 4 · Score: 0.80 · 2026-04-12
Hypotheses and analyses mentioning microglial activation states in their description or question text
No additional research found