gene

PRIMPOL

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRIMPOL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

PRIMPOL: DNA primase and translesion polymerase with roles in mitochondrial DNA replication, oxidative stress response, and neurodegenerative disease

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🧬 Gene Info

Gene Symbol	PRIMPOL
Full Name	DNA Primase/Polymerase
Chromosome	9q34.2
Protein Type	Enzyme
Function	is a unique bifunctional enzyme belonging to the archaeo-eukaryotic primase (AEP) family.
Molecular Weight	58 kDa
Amino Acids	517 aa
Exons	14
UniProt ID	[Q8IY92](https://www.uniprot.org/uniprot/Q8IY92)
Ensembl ID	ENSG00000146859
GeneCards	PRIMPOL
Human Protein Atlas	PRIMPOL
Associated Diseases	Alzheimer's disease, Parkinson's disease, ALS
KG Connections	1 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PRIMPOL — DNA Primase/Polymerase

gene · 3085 words

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Pathway Diagram

graph TD
    PRIMPOL["PRIMPOL"]
    neurodegeneration["neurodegeneration"]
    PRIMPOL -->|"implicated_in"| neurodegeneration
    style PRIMPOL fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
genes-primpol	linked_to	wiki	1.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PRIMPOL in their description or question text

No additional research found