Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AUTOIMMUNE DISEASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | AUTOIMMUNE DISEASE |
graph TD
AUTOIMMUNE_DISEASE[AUTOIMMUNE DISEASE]
AUTOIMMUNE_DISEASE -->|increases_risk| Atherosclerotic_Cardiovascular[Atherosclerotic Cardiovascular Disease]
Aberrant_NLRP_Inflammasome_Act[Aberrant NLRP Inflammasome Activation] -->|causes| AUTOIMMUNE_DISEASE
Berberine[Berberine] -->|treats| AUTOIMMUNE_DISEASE
Tissue_Homeostasis[Tissue Homeostasis] -.protects against.-> AUTOIMMUNE_DISEASE
B_Cells[B Cells] -->|participates in| AUTOIMMUNE_DISEASE
Th17_Cells[Th17 Cells] -->|participates in| AUTOIMMUNE_DISEASE
Descartes_08[Descartes-08] -->|treats| AUTOIMMUNE_DISEASE
B_Cell_Depletion[B Cell Depletion] -->|treats| AUTOIMMUNE_DISEASE| Target | Relation | Type | Str |
|---|---|---|---|
| Atherosclerotic Cardiovascular Disease | increases_risk | disease | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Berberine | treats | compound | 0.85 |
| Tissue Homeostasis | protects_against | process | 0.85 |
| Aberrant NLRP Inflammasome Activation | causes | mechanism | 0.85 |
| Stress-Related Disorders | associated_with | disease | 0.80 |
| STING | associated_with | protein | 0.80 |
| Th17 Cells | participates_in | cell_type | 0.80 |
| miRNA | associated_with | biological_process | 0.80 |
| B Cells | participates_in | cell_type | 0.80 |
| Immune System | associated_with | cell_type | 0.75 |
| Descartes-08 | treats | drug | 0.75 |
| NLRP6 | associated_with | gene | 0.75 |
| Epithelium | associated_with | cell_type | 0.75 |
| B Cell Depletion | treats | mechanism | 0.70 |
| TNF | associated_with | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning AUTOIMMUNE DISEASE in their description or question text
No additional research found