protein

YES1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about YES1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Yes1 — Proto Oncogene Tyrosine Protein Kinase Yes1 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	YES1PROTEIN
Protein Type	Receptor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	tissues including brain, lung, and testis
Subcellular Localization	** \| Plasma membrane, Cytoplasm \|
Molecular Weight	60 kDa
GeneCards	YES1PROTEIN
Human Protein Atlas	YES1PROTEIN
Receptor signaling	Activated by growth factor receptors, integrin receptors, and immune receptors
Synaptic function	Phosphorylates NMDA receptor subunits, PSD-95, and other synaptic proteins
Cellular processes	Regulates cell proliferation, differentiation, survival, migration, and cytoskeletal organization
Alzheimer's Disease	Altered phosphorylation of tau and amyloid precursor protein processing
Parkinson's Disease	Involved in dopaminergic neuron signaling and survival
Cancer	Constitutively active in various cancers
Multi-kinase inhibitors	Dasatinib, bosutinib, saracatinib
Associated Diseases	neurodegeneration
Interactions	AND, CANCER, CYTOKINES, FUS, HNRNPA2B1, IL-6
KG Connections	28 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Yes1 — Proto-Oncogene Tyrosine-Protein Kinase Yes1

protein · 527 words

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Pathway Diagram

graph TD
    YES1PROTEIN["YES1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    YES1PROTEIN -->|"implicated_in"| neurodegeneration
    style YES1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning YES1PROTEIN in their description or question text

No additional research found