gene

WNT3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

Wnt Family Member 3 - a key developmental and signaling gene with implications for neurodegeneration

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🧬 Gene Info

Gene Symbol	WNT3
Aliases	Wnt Family Member 3
Chromosome	12q13.12
Protein Type	Receptor
Function	encodes a key signaling protein involved in embryonic development, tissue patterning, and cellular homeostasis.
Primary Expression	Brain, spinal cord, peripheral tissues
Subcellular Localization	both pre-synaptic and post-synaptic compartments, where it acts in an autocrine and/or paracrine manner
Amino Acids	350 aa
Pathways	WNT, Wnt, wnt, Wnt signaling
UniProt ID	P56703
NCBI Gene ID	7476
Ensembl ID	ENSG00000108379
OMIM	165330
GeneCards	WNT3
Human Protein Atlas	WNT3
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: WNT3 — AlphaFold P56703 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    WNT3["WNT3"]
    neurodegeneration["neurodegeneration"]
    WNT3 -->|"implicated_in"| neurodegeneration
    style WNT3 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
WNT	part_of	gene	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning WNT3 in their description or question text

No additional research found