Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VENTRICULAR ARRHYTHMIAS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | VENTRICULAR ARRHYTHMIAS |
graph TD
VENTRICULAR_ARRHYTHMIAS[VENTRICULAR ARRHYTHMIAS]
VENTRICULAR_ARRHYTHMIAS -->|risk_factor_for| Sudden_Cardiac_Death[Sudden Cardiac Death]
Sympathetic_Remodeling[Sympathetic Remodeling] -->|causes| VENTRICULAR_ARRHYTHMIAS
GJA1[GJA1] -->|causes| VENTRICULAR_ARRHYTHMIAS
Proline_Metabolism[Proline Metabolism] -->|involved_in| VENTRICULAR_ARRHYTHMIAS
Proline[Proline] -->|treats| VENTRICULAR_ARRHYTHMIAS
Mitochondrial_Dysfunction[Mitochondrial Dysfunction] -->|causes| VENTRICULAR_ARRHYTHMIAS
Abnormal_Calcium_Handling[Abnormal Calcium Handling] -->|contributes to| VENTRICULAR_ARRHYTHMIAS
SLC38A2[SLC38A2] -->|target for| VENTRICULAR_ARRHYTHMIAS
LOC100911717[LOC100911717] -->|contributes to| VENTRICULAR_ARRHYTHMIAS| Target | Relation | Type | Str |
|---|---|---|---|
| Sudden Cardiac Death | risk_factor_for | disease | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GJA1 | causes | gene | 0.95 |
| Sympathetic Remodeling | causes | process | 0.95 |
| Proline Metabolism | involved_in | pathway | 0.85 |
| Mitochondrial Dysfunction | causes | process | 0.85 |
| Proline | treats | compound | 0.85 |
| Proline Metabolism | mediates | pathway | 0.85 |
| LOC100911717 | contributes_to | gene | 0.80 |
| GAP43 | associated_with | gene | 0.80 |
| SLC38A2 | therapeutic_target | gene | 0.80 |
| Abnormal Calcium Handling | contributes_to | process | 0.80 |
| Mitochondrial Dysfunction | contributes_to | process | 0.75 |
| Oxidative Stress | contributes_to | process | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning VENTRICULAR ARRHYTHMIAS in their description or question text
No additional research found