Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Tubulin / microtubule dynamics: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| TUBB3 | participates_in | gene | 0.33 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Quantum Coherence Disruption in Cellular Communication | 0.627 | neurodegeneration | Microglia-astrocyte crosstalk amplificat |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 7 hypotheses Top: 0.729
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Biomechanical Impact Profiles and Chronic Traumatic Encephalopathy Phe | clinical | Neurodegeneration | 0.400 | 0.50 | in_silico | proposed | $200,000 |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Meta-analysis of mRNA dysregulation associated with Parkinson's disease and othe [PMID:41183391] | Lin Aung T, Aung YW, Shi X | Biomed Phys Eng Express | 2026 | 1 |
| Single-extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion [PMID:38868956] | Carlos J Nogueras-Ortiz, Erden Eren, Pam | Journal of extracellular vesic | 2024 | 1 |
| Targeting TUBB3 Suppresses Anoikis Resistance and Bone Metastasis in Prostate Ca [PMID:38809199] | Dong B, Gu Y, Sun X, Wang X, Zhou Y, Ron | Adv Healthc Mater | 2024 | 1 |
| Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell [PMID:37450577] | Wang K, Kong F, Qiu Y, Chen T, Fu J, Jin | Autophagy | 2023 | 1 |
| Neuropathology of degenerative ataxias. [PMID:21827883] | Fratkin JD, Vig PJ | Handb Clin Neurol | 2012 | 1 |
| Tubulin mutations in human neurodevelopmental disorders. [PMID:35915025] | Maillard C, Roux CJ, Charbit-Henrion F, | Seminars in cell & development | 2023 | 0 |
| βIII-Tubulin Gene Regulation in Health and Disease. [PMID:35573698] | Duly AMP, Kao FCL, Teo WS, Kavallaris M | Frontiers in cell and developm | 2022 | 0 |
| BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the di [PMID:33404293] | Yazdankhah M, Ghosh S, Shang P, Stepiche | Autophagy | 2021 | 0 |
| Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradat [PMID:30983487] | Ho PW, Leung CT, Liu H, Pang SY, Lam CS, | Autophagy | 2020 | 0 |
| Cell signaling stabilizes morphogenesis against noise. [PMID:31628213] | ["Hagolani P", "Zimm R", "Marin-Riera M" | Development (Cambridge, Englan | 2019 | 0 |
| Benefits of improved air quality on ageing lungs: impacts of genetics and obesit [PMID:30765509] | ["H\u00fcls A", "Sugiri D", "Abramson M" | The European respiratory journ | 2019 | 0 |
| Educational Case: A Uterine Neoplasm: Leiomyoma-A Benign Neoplasm. [PMID:30116773] | ["Magid M"] | Academic pathology | 2018 | 0 |
| ICS teaching module: Ambulatory urodynamic monitoring. [PMID:26594872] | ["Digesu G", "Gargasole C", "Hendricken | Neurourology and urodynamics | 2017 | 0 |
| [ [PMID:28135241] | ["Zimmer E", "Parent M", "Souza D", "Leu | Nature neuroscience | 2017 | 0 |
| Toxins targeting voltage-activated Ca2+ channels and their potential biomedical [PMID:25714378] | ["Gandini M", "Sandoval A", "Felix R"] | Current topics in medicinal ch | 2015 | 0 |
| Integrative analysis reveals disease-associated genes and biomarkers for prostat [PMID:25080090] | ["Li Y", "Vongsangnak W", "Chen L", "She | BMC medical genomics | 2014 | 0 |
| Tau clearance mechanisms and their possible role in the pathogenesis of Alzheime [PMID:24027553] | ["Chesser A", "Pritchard S", "Johnson G" | Frontiers in neurology | 2013 | 0 |
| Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling [PMID:22355118] | ["Swift F", "Franzini-Armstrong C", "\u0 | Proceedings of the National Ac | 2012 | 0 |
| The allometry of chronic myeloid leukemia. [PMID:19362566] | ["Pacheco J", "Traulsen A", "Dingli D"] | Journal of theoretical biology | 2009 | 0 |
| Evidence for wavelike energy transfer through quantum coherence in photosyntheti [PMID:17429397] | ["Engel G", "Calhoun T", "Read E", "Ahn | Nature | 2007 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Tubulin / microtubule dynamics in their description or question text
No additional research found