Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about THYROID HORMONE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | THYROID HORMONE |
graph TD
THYROID_HORMONE["THYROID HORMONE"]
THYROID_HORMONE -->|"inhibits"| Lung_Fibrosis["Lung Fibrosis"]
THYROID_HORMONE -->|"regulates"| BRAIN["BRAIN"]
THYROID_HORMONE -->|"targets"| Astrocytes["Astrocytes"]
THYROID_HORMONE -->|"regulates"| ASTROCYTE["ASTROCYTE"]
THYROID_HORMONE -->|"transports"| Brain["Brain"]
THYROID_HORMONE -.protects against.-> Alveolar_Epithelial_Cells["Alveolar Epithelial Cells"]
THYROID_HORMONE -->|"modulates"| Astroglia["Astroglia"]
THYROID_HORMONE -->|"modulates"| Astroglial_Alterations["Astroglial Alterations"]
DIO2["DIO2"] -->|"activates"| THYROID_HORMONE
MCT8["MCT8"] -->|"transports"| THYROID_HORMONE| Target | Relation | Type | Str |
|---|---|---|---|
| Lung Fibrosis | inhibits | disease | 0.95 |
| BRAIN | regulates | entity | 0.92 |
| MCT8 | interacts_with | protein | 0.90 |
| Astrocytes | targets | cell_type | 0.90 |
| ASTROCYTE | regulates | entity | 0.90 |
| Mitochondrial Biogenesis | associated_with | process | 0.90 |
| Mitochondrial Bioenergetics | associated_with | process | 0.90 |
| Brain | transports | cell_type | 0.90 |
| Apoptosis | associated_with | process | 0.85 |
| Alveolar Epithelial Cells | protects_against | cell_type | 0.85 |
| Astroglial Alterations | modulates | phenotype | 0.85 |
| Astroglia | modulates | cell_type | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MCT8 | associated_with | entity | 0.95 |
| MCT8 | transports | gene | 0.95 |
| Astrocytes | associated_with | cell_type | 0.80 |
| MCT8 | binds_to | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning THYROID HORMONE in their description or question text
No additional research found