gene

SYT8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYT8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

3Outgoing

2Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	SYT8
Chromosome	19p13.3
Protein Family	Synaptotagmin
Function	is a member of the synaptotagmin protein family that functions as a calcium sensor for synaptic vesicle exocytosis and neuroendocrine secretion.
Primary Expression	Neuroendocrine, peripheral tissues
Molecular Weight	46 kDa
Amino Acids	421 aa
Exons	13
UniProt ID	Q9BQW8
NCBI Gene ID	6864
Ensembl ID	ENSG00000173352
GeneCards	SYT8
Human Protein Atlas	SYT8
Hypothalamus	High expression in the paraventricular nucleus and supraoptic nucleus, where it regulates vasopressin and oxytocin secretion
Brainstem	Present in the dorsal motor nucleus of the vagus and nucleus tractus solitarius, areas involved in autonomic control
Associated Diseases	Lymph Node Metastasis, Tumor Size, Vascular Invasion
Interactions	SYNCRIP
KG Connections	5 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SYT8 — AlphaFold Q9BQW8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

syt8

gene · 2252 words

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Pathway Diagram

flowchart TD
    SYT8(["SYT8"])
    INS(["INS"])
    Insulin("Insulin")
    Tumor_Size("Tumor Size")
    Vascular_Invasion("Vascular Invasion")
    Lymph_Node_Metastasis("Lymph Node Metastasis")
    SYNCRIP(["SYNCRIP"])
    neurodegeneration["neurodegeneration"]

    INS -->|"regulates"| SYT8
    SYT8 -->|"participates in"| Insulin
    SYT8 -->|"associated with"| Tumor_Size
    SYT8 -->|"associated with"| Vascular_Invasion
    SYT8 -->|"associated with"| Lymph_Node_Metastasis
    SYNCRIP -->|"interacts with"| SYT8
    SYT8 -->|"implicated in"| neurodegeneration

    style SYT8 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (3)

Target	Relation	Type	Str
Tumor Size	associated_with	phenotype	0.60
Vascular Invasion	associated_with	phenotype	0.60
Lymph Node Metastasis	associated_with	phenotype	0.60

Incoming (2)

Source	Relation	Type	Str
INS	regulates	gene	0.80
SYNCRIP	interacts_with	protein	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SYT8 in their description or question text

No additional research found