entity

SST interneurons

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SST interneurons: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
6Hypotheses
1Analyses
0Outgoing
2Incoming
0Experiments
1Debates

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Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (2)

SourceRelationTypeStr
amyloid-β oligomerscauses (specifically disrupt somatostatin-positive interne)protein0.82
C1Qmodulatesgene0.70

Targeting Hypotheses (6)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Closed-loop transcranial focused ultrasound targeting EC-II 0.948 Alzheimer's disease Circuit-level neural dynamics in neurode
Closed-loop transcranial focused ultrasound targeting EC-II 0.922 Alzheimer's disease Circuit-level neural dynamics in neurode
Closed-loop focused ultrasound targeting EC-II SST interneur 0.900 Alzheimer's disease Circuit-level neural dynamics in neurode
Closed-loop tACS targeting EC-II SST interneurons to block t 0.896 Alzheimer's disease Circuit-level neural dynamics in neurode
Real-time gamma-guided transcranial focused ultrasound targe 0.827 Alzheimer's disease Circuit-level neural dynamics in neurode
Closed-loop tACS targeting entorhinal cortex layer II SST in 0.784 Alzheimer's disease Circuit-level neural dynamics in neurode

Mentioning Analyses (1)

Scientific analyses that reference this entity

Circuit-level neural dynamics in neurodegeneration

neuroscience | 2026-04-03 | 67 hypotheses Top: 1.000

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

Analyze circuit-level changes in neurodegeneration using Allen Institute Neural

closed · Rounds: 4 · Score: 0.95 · 2026-04-03