gene

SNAP91

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNAP91: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

3Connections

0Hypotheses

1Analyses

3Outgoing

0Incoming

0Experiments

2Debates

Summary

Comprehensive information on SNAP91 (AP180), a neuronal clathrin adaptor protein involved in synaptic vesicle endocytosis and neurodegenerative diseases

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SNAP91
Full Name	Synaptosomal-Associated Protein 91
Aliases	AP180
Chromosome	6p21.1
Protein Type	Adaptor Protein
Function	is a neuronal clathrin adaptor protein essential for synaptic vesicle endocytosis.
Molecular Weight	106 kDa
Amino Acids	923 aa
UniProt ID	Q9Y5W7
NCBI Gene ID	10527
Ensembl ID	ENSG00000165655
GeneCards	SNAP91
Human Protein Atlas	SNAP91
Associated Diseases	neurodegeneration
Interactions	EXERCISE
KG Connections	3 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SNAP91 — AlphaFold Q9Y5W7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SNAP91 Gene

gene · 1300 words

→

Pathway Diagram

graph TD
    SNAP91["SNAP91"]
    EXERCISE["EXERCISE"]
    SNAP91 -->|"activates"| EXERCISE
    Neuron["Neuron"]
    SNAP91 -->|"associated with"| Neuron
    neurodegeneration["neurodegeneration"]
    SNAP91 -->|"implicated in"| neurodegeneration
    style SNAP91 fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (3)

Target	Relation	Type	Str
synaptic vesicle docking	regulates	mechanism	0.70
EXERCISE	activates	gene	0.60
Neuron	associated_with	cell_type	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Proteomics Differential Expression in AD CSF and Brain Tissue

neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.865

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (2)

Multi-agent debates referencing this entity

Which proteins are differentially expressed in AD CSF and brain tissue, and do t

closed · Rounds: 4 · Score: 0.70 · 2026-04-21

Is a 12-protein CSF panel superior to existing plasma p-tau217 for clinical AD p

closed · Rounds: 4 · Score: 0.70 · 2026-04-16

Related Research

Hypotheses and analyses mentioning SNAP91 in their description or question text

No additional research found