Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SCFA depletion: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| h-gap-2f2e5b80-m2 | involves | hypothesis | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| plasma LPS-binding protein separates causal from compensator | 0.346 | neurodegeneration | How does gut microbiome dysbiosis contri |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 3 hypotheses Top: 0.346
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Gastrodin regulates the TLR4/TRAF6/NF-κB pathway to reduce neuroinflammation and [PMID:38552431] | Wang W, Wang Y, Wang F, Xie G, Liu S, Li | Phytomedicine : international | 2024 | 0 |
| Gastrodin regulates the TLR4/TRAF6/NF-κB pathway to reduce neuroinflammation and [PMID:38552431] | Wang W, Wang Y, Wang F, Xie G, Liu S, Li | Phytomedicine : international | 2024 | 0 |
| Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting n [PMID:36601662] | ["Zhang Di", "Jing Bei", "Chen Zhen-Ni", | CNS neuroscience & therapeutic | 2023 | 0 |
| Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation [PMID:37435081] | Park, Hwang, Lee, Jang, Jeong et al. | Frontiers in immunology | 2023 | 0 |
| Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation [PMID:37435081] | Unknown | Frontiers in immunology | 2023 | 0 |
| Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting n [PMID:36601662] | ["Zhang Di", "Jing Bei", "Chen Zhen-Ni", | CNS neuroscience & therapeutic | 2023 | 0 |
| Early glycolytic reprogramming controls microglial inflammatory activation. [PMID:34107997] | ["Cheng Junjie", "Zhang Rong", "Xu Zhiro | Journal of neuroinflammation | 2021 | 0 |
| Early glycolytic reprogramming controls microglial inflammatory activation. [PMID:34107997] | ["Cheng Junjie", "Zhang Rong", "Xu Zhiro | Journal of neuroinflammation | 2021 | 0 |
Multi-agent debates referencing this entity
closed · Rounds: 3 · Score: 0.75 · 2026-04-26
closed · Rounds: 3 · Score: 0.75 · 2026-04-26
closed · Rounds: 4 · Score: 0.78 · 2026-04-26
Hypotheses and analyses mentioning SCFA depletion in their description or question text
No additional research found