gene

RPS8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPS8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

Gene page for RPS8 (Ribosomal Protein S8), a component of the 40S ribosomal subunit essential for protein synthesis and associated with Diamond-Blackfan anemia.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	RPS8
Aliases	Ribosomal Protein S8
Chromosome	1p34.2
Function	encodes a protein of 208 amino acids.
Primary Expression	neurons and glial cells, contributing to the high protein synthesis demands of neural tissue
Molecular Weight	24.1 kDa
Amino Acids	208 aa
Ensembl ID	ENSG00000142937
GeneCards	RPS8
Human Protein Atlas	RPS8
Bone marrow	High expression in hematopoietic progenitor cells
Brain	Particularly elevated in regions with active protein synthesis
Muscle	High expression in skeletal muscle
Proliferating cells	Elevated expression in rapidly dividing cells
Associated Diseases	neurodegeneration
KG Connections	1 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

RPS8 Gene

gene · 1107 words

→

Pathway Diagram

flowchart TD
    N0["RPS8"]
    N1["RPS18"]
    N1 -->|"upregulates"| N0
    N2["neurodegeneration"]
    N0 -->|"implicated in"| N2

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 gene

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
RPS18	upregulates	gene	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RPS8 in their description or question text

No additional research found